Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?

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Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?

Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency. The purpose of this study is to determine if functional single nucleotide polymorphisms (SNPs) in immune-modulating genes pre-dispose infants to NEC. After Institutional Review Board approval and parental consent, buccal swabs were collected for DNA extraction. TaqMan allelic discrimination assays and BglII endonucleas...

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Single Nucleotide Polymorphisms within Calcineurin-Encoding Genes are Associated with Response to Aerobic Training in Han Chinese Males

Calcineurin, which functions in calcium signaling, is expressed in skeletal and cardiac muscle and has been linked to sensitivity to muscle strength training. It is also proposed to contribute to individual aerobic endurance. To investigate the relationship between calcineurin-encoding genes and aerobic endurance traits, 126 young-adult Han Chinese males were enrolled in an aerobic exercise tra...

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[Factors associated with necrotizing enterocolitis].

OBJECTIVE To evaluate the features of clinical presentation of neonatal necrotizing enterocolitis and its associated factors. METHODS Retrospective study of the cases of neonatal necrotizing enterocolitis (n = 56) diagnosed at Neonatal Intensive Care Unit Lagoa (NICU), between December 1986 and July 1992. Diagnosis and stages of the disease followed the modified Bell's criteria. Diagnosis and...

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Transfusion-associated Necrotizing Enterocolitis.

From October 2010 to December 2015, we screened a total of 1716 babies. 809 babies were from well-baby nurseries and 907 babies were from neonatal intensive care unit. 299 babies failed the first screen, but only 66 out of 299 appeared for rescreen. Eighteen babies failed the rescreen and were recommended BERA testing. However, none of the babies turned up for BERA testing or could not be track...

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Transfusion-associated Necrotizing Enterocolitis

From October 2010 to December 2015, we screened a total of 1716 babies. 809 babies were from well-baby nurseries and 907 babies were from neonatal intensive care unit. 299 babies failed the first screen, but only 66 out of 299 appeared for rescreen. Eighteen babies failed the rescreen and were recommended BERA testing. However, none of the babies turned up for BERA testing or could not be track...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2015

ISSN: 2045-2322

DOI: 10.1038/srep18369